Tag: RDMM

Solve-RD Seeding Grant recipient Michela Ori successfully received competitive grant from the Telethon Foundation (Italy)

Michela Ori and her group at the Department of Biology, University of Pisa, Italy have received Seeding Grant funding via the Solve-RD Rare Disease Models & Mechanisms Network (RDMM-Europe) program in August 2020.

Based on preliminary data obtained with the Solve-RD Seeding Grant, Michela's lab has successfully applied for a competitive grant from the Italian Telethon Foundation. The project with the title "Modeling Pitt-Hopkins syndrome and new pathogenetic variants of TCF4 by gene editing: a step forward toward personalized medicine (acronim: HOPeFOR)" started in March 2023.

Solve-RD partner Antonio Vitobello from CHU Dijon who initially identified those novel gene variants in patients with facial dysmorphism and who was matched to Michela Ori's group via RDMM-Europe will be a collaborator in this project.

More info (in Italian) here.

 

Solve-RD Seeding Grant recipient Alessandro Sessa successfully obtained a competitive grant from the Telethon/CARIPLO alliance in Italy.

Alessandro Sessa and his group at the IRCCS Ospedale San Raffaele, Milano, Italy have received Seeding Grant funding in April 2021 to validate rare missense variants identified by Siddharth Banka at the Manchester Centre for Genomic Medicine, UK. Based on preliminary data generated with the Solve-RD funding Alessandro Sessa successfully applied for a competitive grant from the Telethon/CARIPLO alliance (Italy) to continue the analysis (250.000€/2 years). The call (the first of its kind) was in support of basic research projects focusing on the study of genes/gene families, proteins, and RNA molecules whose function is unknown in rare diseases of genetic and non-genetic origin.