What is the registry?
The RDMM-Europe registry is an online registration tool and a database of European Model Organism Investigators and the specific genes they study. The RDMM-Europe Scientific Advisory Committee uses the registry to determine which scientists are doing work relevant to a newly identified human disease gene. Registrants who meet the criteria for a given gene will be invited to apply for a Seeding Grant.
What is the purpose of the registry?
The purpose of the RDMM-Europe registry is to collect information about Model Organism Investigators, focusing on genes they are studying. The registry will be used by the RDMM-Europe Scientific Advisory Committee and the Solve-RD Project Management Office to look for orthologues of a newly identified human disease gene. Model Organism Investigators studying the identified genes will be invited to apply for a Seeding Grant.
Furthermore, clinicians will also be able to query the database on their own in order to find a scientific partner for the functional validation of a new gene.
What is the process for making a Seeding Grant award?
Briefly, the RDMM-Europe Scientific Advisory Committee (SAC) will attempt to match a new disease gene with as many Model Organism Investigators as possible, based on the genes that Model Organism Investigators have self-declared in the registry. The Project Management Office will then invite the Model Organism Investigator to respond to the respective call for tender of the Solve-RD brokerage service and to submit a Seeding Grant application for functional studies of the respective gene. The SAC will review the applications (within two weeks) and will ask the clinician to establish a connection with the selected Model Organism Investigator.
Following a successful connection, clinician and Model Organism Investigator will be contacted by the Project Management Office to sign a Memorandum of Agreement. In addition, the model organism lab will sign a subcontract in order to receive the Seeding Grant of 20,000 EUR to functionally validate the new disease gene.
Who should register?
All European Model Organism Investigators should register if they want to be considered for a Solve-RD Seeding Grant and/or be visible for queries made by clinicians searching for experts for specific genes.
Who will see the information I submit?
The RDMM-Europe Scientific Advisory Committee and the Solve-RD Project Management Office will use the registry to identify candidates that will be invited to respond to a call for tender.
Your information (name, institution, matching gene/pathway and model organism) will also be seen by anyone who uses the query tool (will be set up soon) and searches for experts for specific genes/pathways. Your information will appear only when it matches the search criteria.